The red half of London Arsenal had secured top spot in Europa League Group H on Thursday despite slumping to a 1-0 defeat at struggling German side Cologne.
Arsenal were confirmed as group winners following Red Star Belgrade’s 0-0 draw with Bate Borisov.
The Frenchman made 11 changes to the team that beat Tottenham Hotspur in last weekend’s north London derby, with starts handed to Olivier Giroud, Jack Wilshere and Danny Welbeck.
Mario Balotelli struck twice as Nice booked their place in the Europa League knock-out stages.
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The French side needed a victory against Belgian side Zulte Waregem to secure their passage — and the Italian duly delivered.
Balotelli opened the scoring on five minutes, before converting a 31st-minute penalty.
Brian Hamalainen pulled one back near the end, but Adrien Tameze made it 3-1 to Nice five minutes from time to ensure the Ligue 1 side finished second.
First place Group K had already been secured by Lazio, who had maximum points coming into the penultimate round of fixtures.
But, despite an impressive performance, the Italian giants could only manage a 1-1 draw at home against Vitesse Arnhem, thanks to Luis Alberto’s stunning equaliser.
AC Milan were big winners as they qualified for the knock-out stage.
Andre Silva and impressive youngster Patrick Cutrone hit a brace apiece as the seven-time European champions came from a goal down to win 5-1.